Comparative Analysis of Amino-acid sequences based on Rough Set Theory and Change of Representation
نویسندگان
چکیده
Protein structure analysis from DNA sequences is an important and fast growing area in both computer science and biochemistry. One of the most important problems is that two proteins, both of which have the similar three-dimensional structure, have different functions, such as ll/sozyme and lactalbumin. In such cases, comparative analysis of both amino acid sequences is effective to detect the functional and structural differences. In this paper, we introduce a s~stem, rolled MWI.5 (Molecular biologists’ Workbench version 1.5), which eJztracts differential knowledge from amino-acid sequences by using rowh-set based classification, statistical analysis and change of representation. This method is applied to the follo~dng two domain: comparative analysis of lysozyme and a-lactalbumin, and analysis of immunoglobulin structure. The results show that several interesting results from amino-acid sequences, are obtained which have not been reported before.
منابع مشابه
Automated Discovery of Functional Components of Proteins from Amino-Acid Sequences Based on Rough Sets and Change of Representation
Protein structure analysis from DNA sequences is an important and fast growing area in both computeT science and biochemistry. Although interesting approaches have been studied, it is very dificult to capture the characteristics of protein, since even a simple protein are made of more than 100 amino acids, which makes biochemical experiments very dificult to detect functional components. For th...
متن کاملT-Rough Sets Based on the Lattices
The aim of this paper is to introduce and study set- valued homomorphism on lattices and T-rough lattice with respect to a sublattice. This paper deals with T-rough set approach on the lattice theory. The result of this study contributes to, T-rough fuzzy set and approximation theory and proved in several papers. Keywords: approximation space; lattice; prime ideal; rough ideal; T-rough set; set...
متن کاملPhylogenetic and sequence analysis of the growth hormone gene of two sturgeons, Huso huso and Acipenser Gueldenstaedtii
In this study, the cDNA Growth Hormone (cGH) of the Belugasturgeon (Husohuso) and Russian sturgeon (Acipensergueldenstaedtii) were cloned and sequenced, and phylogenetic relationships were examined using nucleic acid and amino acid sequences. The nucleotide sequence of the Beluga GH has an open reading frame of 645 nucleotides encoding a protein 214 amino acid residues. The signal peptide cleav...
متن کاملReduction of DEA-Performance Factors Using Rough Set Theory: An Application of Companies in the Iranian Stock Exchange
he financial management field has witnessed significant developments in recent years to help decision makers, managers and investors, to made optimal decisions. In this regard, the institutions investment strategies and their evaluation methods continuously change with the rapid transfer of information and access to the fi- nancial data. When information is available ...
متن کاملA New Approach for Knowledge Based Systems Reduction using Rough Sets Theory (RESEARCH NOTE)
Problem of knowledge analysis for decision support system is the most difficult task of information systems. This paper presents a new approach based on notions of mathematical theory of Rough Sets to solve this problem. Using these concepts a systematic approach has been developed to reduce the size of decision database and extract reduced rules set from vague and uncertain data. The method ha...
متن کامل